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San Francisco- 10
Buffalo- 35
BUF: Josh Allen- 13 out of 17 passes for 148 yards, two touchdown passes, a rushing touchdown and a touchdown reception
Allen becomes the first player in NFL history to throw a touchdown pass, score a rushing touchdown and catch a touchdown pass in a single game.
James Cook- 14 carries for 107 yards and a rushing touchdown
SF: In the second quarter, running back Christian McCaffrey suffered an injury to his right knee. The injury happened after McCaffrey took a pitch from quarterback Brock Purdy where he barely moved with the ball before slowing to a limp, then sliding into the snow covered Highmark Stadium, avoiding contact and signaled for medical attention. It is feared that McCaffrey's injury could be season-ending.
Philadelphia- 24
Baltimore- 19
PHI: Saquon Barkley- 23 carries for 107 yards and a rushing touchdown
Tampa Bay- 26
Carolina- 23 overtime
CAR: Bryce Young- 26 out of 46 passes for 298 yards, a touchdown pass and a rushing touchdown
LA Rams- 21
New Orleans- 14
Arizona- 22
Minnesota- 23
Pittsburgh- 44
Cincinnati- 38
PIT: Russell Wilson- 29 out of 38 passes for 414 yards, three touchdown passes and an interception
Tennessee- 19
Washington- 42
LA Chargers- 17
Atlanta- 13
Indianapolis- 25
New England- 24
Houston- 23
Jacksonville- 20
JAX: In the first half, quarterback Trevor Lawrence suffered a concussion after taking a nasty hit from a Jaguars defender.
Seattle- 26
NY Jets- 21
SEA: Leonard Williams- recorded two sacks and scored an interception-return touchdown